blood.foundation
Terms

Glossary

The vocabulary of blood science, in plain words.

Plasma
The liquid part of blood: water, salts and proteins.
Serum
Plasma with the clotting proteins removed.
Red cell
Erythrocyte: the oxygen carrier. It has no nucleus and lives about 120 days.
White cell
Leukocyte: any of the immune cells carried in blood.
Platelet
A cell fragment that starts clot formation.
Haemoglobin
The iron-containing protein in red cells that binds oxygen.
Haematocrit
The proportion of blood volume taken up by red cells — typically about 40 to 45 per cent.
Haematopoiesis
The formation of blood cells, in the bone marrow.
Anaemia
Too little haemoglobin to carry enough oxygen.
Antigen (blood group)
A molecule on the red cell surface that differs between people.
ABO
The most important blood group system: groups A, B, AB and O.
Rh
The second most important system. “Positive” and “negative” refer to its D antigen.
Crossmatch
A laboratory test mixing patient plasma with the cells to be transfused, to check compatibility.
Coagulation cascade
The chain of plasma proteins that ends in a fibrin clot.
Fibrin
The protein mesh that holds a clot together.
Haemophilia
An inherited lack of a clotting factor.
Thrombosis
A clot forming where it should not, inside a vessel.
Anticoagulant
A substance that prevents clotting.
Leukaemia
Cancer of the blood-forming cells.
Component therapy
Giving only the part of blood a patient needs: red cells, platelets or plasma.